Nexium is indicated for the treatment of erosive gastritis (damage to lower esophagus by acid reflux from stomach), moderate to severe heartburn, and reduction in reoccurance of duodenal ulcers. It acts by inhibiting proton pumps (hydrogen ion) in the stomach. This inhibition reduces the amount of acid produced by the stomach.
Nexium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Nexium may also be given to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Nexium is not for immediate relief of heartburn symptoms.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Some common foods that we eat and drink, stimulate increased stomach acid secretion setting the stage for heartburn. Over-the-counter medications also may precipitate heartburn. Examples of these irritants include:
Aspirin (Bayer, etc.)
Buprofen (Motrin, Advil, Nuprin, etc.)
Naproxen (Naprosyn, Aleve)
Acidic juices (grapefruit, orange, pineapple)
Acidic foods (tomatoes, grapefruit, and oranges)
Three 14-day courses of treatment Nexium 24HR works by blocking acid at the source, giving you 24 hours of protection from frequent heartburn Use as directed, may take 1-4 days for full effect. Trust the purple pill!
Most people can take Nexium (esomeprazole) without any noticeable day-to-day side effects.
Nexium (esomeprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need quicker relief.
Nexium (esomeprazole) is inexpensive, with over-the-counter and generic options.
Coupons are available for the brand name - speak to your doctor or pharmacist.
The packet form is a good option if you have trouble swallowing pills.They can be mixed with water for easier swallowing.
Active Ingredients: Esomeprazole - 20 mg Inactive Ingredients: Corn Starch, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, Ferric Oxide, Gelatin, Glyceryl Monostearate, Hydroxypropyl Cellulose, Hypromellose, Magnesium Stearate, Methacrylic Acid Copolymer, Pharmaceutical Ink, Polysorbate 80, Sucrose, Talc, Titanium Dioxide, Triethyl Citrate.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Do not use if seal under bottle cap imprinted with "sealed for your protection" or yellow band around the center of each capsule is broken or missing.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Since Nexium belongs to a group of proton pump inhibitors, it is potent to reduce the levels of acid produced within the stomach. As a result, the medication is commonly used to improve related conditions, including Zollinger-Ellison syndrome, esophagitis, gastroesophageal reflux disease and other health disorders related to excess acid production.
The treatment can also be recommended as a preventative medication to warn gastric ulcers provoked by nonsteroidal anti-inflammatory drugs of helicobacter pylori infection. However, the drug will not improve the symptoms of sudden heartburn.
Additionally, Esomeprazole, an active component of the remedy, can be administered in other instances, not mentioned in the safety guide.
I currently take 40 mg capsules. I used to vomit and belch a lot, but Nexium stopped these symptoms.
By Christine J (Lawton, OK)
Since childhood I have had excess stomach acid and developed GERD in early adulthood.
Nexium is by far the best medication I have ever used.
By Susan J (Portland, OR)
Take Nexium exactly as directed on the label, or as prescribed by your doctor. Do not take this medicine in larger or smaller amounts or for longer than recommended.
This medicine is usually given for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time.
Use Nexium with water 1-2 hours before a meal.
Take each dose with a full glass (8 ounces) of water.
Nexium should be taken at least one hour before a meal.
Do not crush or chew a delayed-release capsule. However to make swallowing easier, you may open the Nexium capsule and sprinkle the medicine into a spoonful of pudding or applesauce. Swallow right away without chewing. Do not save the mixture for later use.
Nexium can be given through a nasogastric (NG) feeding tube. Open the capsule and sprinkle the medicine into a 60-milliliter syringe. Mix in 50 milliliters of water. Place the plunger into the syringe and shake the mixture well. Make sure there are no medicine granules stuck in the tip of the syringe. Attach the syringe to the NG tube and push the plunger down to empty the syringe into the tube. Then flush the tube with more water to wash the contents down.
Gastric Acid Reduction Nexium - Esomeprazole is a PPI that reduces gastric acid secretion in Gastric hydrogen potassium ATPase through inhibition in gastric parietal cells. By inhibiting the functioning of this enzyme, the Esomeprazole prevents formation of gastric acid.
Helicobacter pylori eradication - When antibiotics clarithromycin and amoxicillin (or metronidazole in penicillin-hypersensitive patients) are combined with Esomeprazole this is referred to as triple therapy for the eradication of Helicobacter pylori. This is a very common treatment for peptic and duodenal ulcers infected by H. pylori.
Dosage Forms - Esomeprazole in pill form is available in strengths of 20 mg and 40 mg. Esomeprazole pills are enteric-coated, due to the acidic conditions of the stomach and rapid degradation of the drug. This is achieving the multiple-unit pellet system of Esomeprazole.
Multiple unit pellet system - Esomeprazole "multiple unit pellet system" (MUPS) are formulated capsules. Each capsule consists of very small enteric-coated pellets of esomeprazole within an outer shell. When esomprazole reaches the stomach the contents swell from the water absorption causing the outer shell to burst, releasing the medicine. For most patients, there is no difference with taking the traditional entreric-coated over the multiple unit pellet system. Patients that require a feeding tube or have dysphagia condition that makes it difficult to swallow may find that the MUPS method of taking Espmprazole more comfortable..
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